Doozla is a drawing application (Mac OS X only) designed for children from Plasq, the geniuses behind Skitch and Comic Life. There are 4 main ways to use Doozla: free drawing on a plain white background, drawing on a webcam capture, drawing on one of the included background pictures, and coloring-book mode.

The interface is fullscreen and child friendly since it provides large icons and a simple feature set. There are standard tools like a color chooser, eraser, paint bucket, and ellipse tool, and clicking any of the tools triggers a jolly voice to vocalize the name of the tool or color that was chosen.

Unfortunately Doozla only saves drawings in .doozla files (not .jpgs, .gifs, etc.), so it's not very easy to share creations. However, you can print the drawing to a standard printer or to a PDF.

Doozla costs $24.95, but a 30-day trial is available.