SlickRun is my newest favorite utility. It's a very small and simple application launcher, but packs some pretty powerful features into it's tiny self. Along with allowing you to assign keywords to applications and launch them, you can quickly navigate to both local folders on your filesystem as well as websites. Simply hit the SlickRun hotkey combination, type your destination and press Enter, and whammo - you're there. SlickRun also contains a very useful Jot application for taking notes. It automatically saves so you don't need to remember to, will accept any text that is dragged and dropped onto it, and timestamps entries to make finding them again easier. It also contains a Find function.